Month: February 2022

Makowski lab receives R01 from NCI to study genetic variants in breast cancer.


We are happy to announce that Liza Makowski was awarded an R01 from the NCI which scored a 2%. The proposal is entitled “Determining susceptibility loci in triple negative breast cancer using a novel pre-clinical model.” Co-investigators Drs. Rob Williams, Lu Lu, D. Neil Hayes, and David Ashbrook at UTHSC and Dr. Carey Anders at… Read More

Mehdi Chaib awarded F31NRSA Pre-doctoral Fellowship award from the National Cancer Institute (NCI)


Mehdi Chaib, graduate student in Makowski Lab, was awarded a 3 year F31 predoctoral NRSA fellowship from the NCI in Dec of 2021. His proposal entitled “PKC agonism restricts innate immune suppression and promotes antigen cross-presentation in Triple Negative Breast Cancer” scored a 3%. We are so proud of him! Congratulations!

Excited to share our new manuscript led by Mehdi Chaib in Cancer Letters on PKC agonism


Makowski lab graduate student Mehdi Chaib has published “PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 antibody therapy to activate CD8 + T cells in breast cancer” in Cancer Letters (here). Congratulations Mehdi! Highlights: •PKC agonism suppresses murine breast cancer tumor growth in vivo. •PKC agonism impairs MDSC expansion, trafficking, and suppressive… Read More