Month: February 2022


Makowski lab receives R01 from NCI to study genetic variants in breast cancer.

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We are happy to announce that Liza Makowski was awarded an R01 from the NCI which scored a 2%. The proposal is entitled “Determining susceptibility loci in triple negative breast cancer using a novel pre-clinical model.” Co-investigators Drs. Rob Williams, Lu Lu, D. Neil Hayes, and David Ashbrook at UTHSC and Dr. Carey Anders at… Read More

Mehdi Chaib awarded F31NRSA Pre-doctoral Fellowship award from the National Cancer Institute (NCI)

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Mehdi Chaib, graduate student in Makowski Lab, was awarded a 3 year F31 predoctoral NRSA fellowship from the NCI in Dec of 2021. His proposal entitled “PKC agonism restricts innate immune suppression and promotes antigen cross-presentation in Triple Negative Breast Cancer” scored a 3%. We are so proud of him! Congratulations!

Excited to share our new manuscript led by Mehdi Chaib in Cancer Letters on PKC agonism

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Makowski lab graduate student Mehdi Chaib has published “PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 antibody therapy to activate CD8 + T cells in breast cancer” in Cancer Letters (here). Congratulations Mehdi! Highlights: •PKC agonism suppresses murine breast cancer tumor growth in vivo. •PKC agonism impairs MDSC expansion, trafficking, and suppressive… Read More