Category: Uncategorized


Congratulations to Dr. Mehdi Chaib for Makowski Lab’s recent publication in Science Advances on PKCdelta in monocytes in cancer immunotherapy

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Congrats to Mehdi, my former graduate student, on his last paper from this doctoral thesis recently published in Science Advances. It took a great team to complete this important body of work demonstrating that protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer. Here is the PubMed link. Great job… Read More

Happy 2024! Great news, we are hiring!

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Please apply https://ut.taleo.net/careersection/uthsc_post-docs/jobdetail.ftl?job=230000027X&tz=GMT-06%3A00&tzname=America%2FChicago

Congrats to Makowski lab for 3 Million dollar award from the Mark Foundation for Cancer Research entitled “Inflammatory Drivers of The Obesity-Cancer Connection”

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We are hiring for our newly funded NCI U01 to study obesity, protective immunity, and breast cancer risk.

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Come work with us! Link to posting here.

We can’t wait to work with NCI’s Metabolic Dysregulation and Cancer Risk Program: A Transdisciplinary Approach to Obesity-Associated Cancer Research program.

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Very excited to conduct this work on my project entitled Determining the Contribution of Microbial-Derived Metabolites to Protective Immunity in Obesity-Driven Cancer Risk with MPIs Jeff Rathmell and Joseph Pierre, and many other collaborators. This is a dream project! These studies will increase understanding of obesity-associated cancer risk and point to potential interventions to alleviate… Read More

Check out our new paper led by Dr. Laura Sipe, PhD in eLife on immunotherapy response in pre-clinical models of breast cancer after bariatric surgery

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Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery. Link HERE

Happy Graduation to Dr. Mehdi Chaib, PhD – Commencement 2022

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Mehdi Chaib, PhD (@ChaibImmune) has completed his doctoral studies in the Makowski lab and has joined the lab of Jim Allison, PhD at MD Anderson to complete his post-doctoral studies.

UTHSC-led team receives $5.2 million for study of link between obesity – Press release from UTHSC for our new U01 grant!

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Congratulations to Dr. Mehdi Chaib, Ph.D.

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5/11/2022- Mehdi Chaib successfully defended his thesis entitled “Targeting Myeloid Protein Kinase C Signaling to Overcome Immune Suppression and Improve Immunotherapy in Cancer”. We can’t wait to see you walk in August!

Press release is out for our new R01 to study breast cancer genetics

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UTHSC Team Receives $2 Million For Breast Cancer Genetics Research